| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 30/09/22 17:30 | 30/09/22 17:15 | SC Paderborn 07 | SV Darmstadt 98 | 1-2 | 2 - 4 points |
| 30/09/22 17:30 | 30/09/22 17:15 | Hannover 96 | Hamburger SV | 1-2 | 2 - 4 points |
| 01/10/22 12:00 | 01/10/22 11:45 | Fortuna Düsseldorf | Arminia Bielefeld | 4-1 | 2 - 4 points |
| 01/10/22 12:00 | 01/10/22 11:45 | SpVgg Greuther Fürth | SV Sandhausen | 1-1 | 2 - 4 points |
| 01/10/22 12:00 | 01/10/22 11:45 | Holstein Kiel | FC Hansa Rostock | 1-1 | 2 - 4 points |
| 01/10/22 19:30 | 01/10/22 19:15 | FC St. Pauli | 1. FC Heidenheim 1846 | 0-0 | 2 - 4 points |
| 02/10/22 12:30 | 02/10/22 12:15 | 1. FC Magdeburg | Jahn Regensburg | 1-0 | 2 - 4 points |
| 02/10/22 12:30 | 02/10/22 12:15 | 1. FC Kaiserslautern | Eintracht Braunschweig | 1-1 | 2 - 4 points |
| 02/10/22 12:30 | 02/10/22 12:15 | Karlsruher SC | 1. FC Nürnberg | 3-0 | 2 - 4 points |