Schedule
| Competition | Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|---|
| DFB | 18/01/22 17:30 | 18/01/22 17:20 | 1. FC Köln | Hamburger SV | 4-5a.PSO | 1 - 5 points |
| DFB | 18/01/22 17:30 | 18/01/22 17:20 | TSV 1860 Munich | Karlsruher SC | 0-1 | 1 - 5 points |
| DFB | 18/01/22 19:45 | 18/01/22 19:35 | FC St. Pauli | Borussia Dortmund | 2-1 | 1 - 5 points |
| DFB | 18/01/22 19:45 | 18/01/22 19:35 | VfL Bochum | FSV Mainz 05 | 3-1 | 1 - 5 points |
| DFB | 19/01/22 17:30 | 19/01/22 17:20 | Hannover 96 | Bor. Mönchengladbach | 3-0 | 1 - 5 points |
| DFB | 19/01/22 17:30 | 19/01/22 17:20 | RB Leipzig | FC Hansa Rostock | 2-0 | 1 - 5 points |
| DFB | 19/01/22 19:45 | 19/01/22 19:35 | 1899 Hoffenheim | SC Freiburg | 1-4 | 1 - 5 points |
| DFB | 19/01/22 19:45 | 19/01/22 19:35 | Hertha BSC | 1. FC Union Berlin | 2-3 | 1 - 5 points |
| 2.BL | 21/01/22 17:30 | 21/01/22 17:20 | Hamburger SV | FC St. Pauli | 2-1 | 1 - 3 points |
| 2.BL | 21/01/22 17:30 | 21/01/22 17:20 | Fortuna Düsseldorf | 1. FC Nürnberg | 0-1 | 1 - 3 points |
| GER1 | 21/01/22 19:30 | 21/01/22 19:20 | Eintracht Frankfurt | Arminia Bielefeld | 0-2 | 3 - 5 points |
| 2.BL | 22/01/22 12:30 | 22/01/22 12:20 | FC Ingolstadt | SV Darmstadt 98 | 0-2 | 1 - 3 points |
| 2.BL | 22/01/22 12:30 | 22/01/22 12:20 | SC Paderborn 07 | Werder Bremen | 3-4 | 1 - 3 points |
| 2.BL | 22/01/22 12:30 | 22/01/22 12:20 | FC Hansa Rostock | 1. FC Heidenheim 1846 | 0-0 | 1 - 3 points |
| GER1 | 22/01/22 14:30 | 22/01/22 14:20 | Bor. Mönchengladbach | 1. FC Union Berlin | 1-2 | 3 - 5 points |
| GER1 | 22/01/22 14:30 | 22/01/22 14:20 | Bayer 04 Leverkusen | FC Augsburg | 5-1 | 3 - 5 points |
| GER1 | 22/01/22 14:30 | 22/01/22 14:20 | 1899 Hoffenheim | Borussia Dortmund | 2-3 | 3 - 5 points |
| GER1 | 22/01/22 14:30 | 22/01/22 14:20 | SC Freiburg | VfB Stuttgart | 2-0 | 3 - 5 points |
| GER1 | 22/01/22 14:30 | 22/01/22 14:20 | SpVgg Greuther Fürth | FSV Mainz 05 | 2-1 | 3 - 5 points |
| GER1 | 22/01/22 17:30 | 22/01/22 17:20 | VfL Bochum | 1. FC Köln | 2-2 | 3 - 5 points |
| 2.BL | 22/01/22 19:30 | 22/01/22 19:20 | Erzgebirge Aue | FC Schalke 04 | 0-5 | 1 - 3 points |
| 2.BL | 23/01/22 12:30 | 23/01/22 12:20 | Hannover 96 | Dynamo Dresden | 0-0 | 1 - 3 points |
| 2.BL | 23/01/22 12:30 | 23/01/22 12:20 | Jahn Regensburg | Holstein Kiel | 1-2 | 1 - 3 points |
| GER1 | 23/01/22 14:30 | 23/01/22 14:20 | RB Leipzig | VfL Wolfsburg | 2-0 | 3 - 5 points |
| GER1 | 23/01/22 16:30 | 23/01/22 16:20 | Hertha BSC | FC Bayern Munich | 1-4 | 3 - 5 points |
| 2.BL | 08/02/22 17:30 | 08/02/22 17:20 | Karlsruher SC | SV Sandhausen | 0-2 | 1 - 3 points |