Schedule
| Competition | Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|---|
| 2.BL | 03/12/21 17:30 | 03/12/21 17:20 | Werder Bremen | Erzgebirge Aue | 4-0 | 1 - 3 points |
| 2.BL | 03/12/21 17:30 | 03/12/21 17:20 | SV Darmstadt 98 | Fortuna Düsseldorf | 1-3 | 1 - 3 points |
| GER1 | 03/12/21 19:30 | 03/12/21 19:20 | 1. FC Union Berlin | RB Leipzig | 2-1 | 3 - 5 points |
| 2.BL | 04/12/21 12:30 | 04/12/21 12:20 | 1. FC Nürnberg | Holstein Kiel | 2-1 | 1 - 3 points |
| 2.BL | 04/12/21 12:30 | 04/12/21 12:20 | SV Sandhausen | SC Paderborn 07 | 1-1 | 1 - 3 points |
| 2.BL | 04/12/21 12:30 | 04/12/21 12:20 | FC Hansa Rostock | FC Ingolstadt | 1-1 | 1 - 3 points |
| GER1 | 04/12/21 14:30 | 04/12/21 14:20 | FSV Mainz 05 | VfL Wolfsburg | 3-0 | 3 - 5 points |
| GER1 | 04/12/21 14:30 | 04/12/21 14:20 | 1899 Hoffenheim | Eintracht Frankfurt | 3-2 | 3 - 5 points |
| GER1 | 04/12/21 14:30 | 04/12/21 14:20 | Bayer 04 Leverkusen | SpVgg Greuther Fürth | 7-1 | 3 - 5 points |
| GER1 | 04/12/21 14:30 | 04/12/21 14:20 | Arminia Bielefeld | 1. FC Köln | 1-1 | 3 - 5 points |
| GER1 | 04/12/21 14:30 | 04/12/21 14:20 | FC Augsburg | VfL Bochum | 2-3 | 3 - 5 points |
| GER1 | 04/12/21 17:30 | 04/12/21 17:20 | Borussia Dortmund | FC Bayern Munich | 2-3 | 3 - 5 points |
| 2.BL | 04/12/21 19:30 | 04/12/21 19:20 | FC St. Pauli | FC Schalke 04 | 2-1 | 1 - 3 points |
| 2.BL | 05/12/21 12:30 | 05/12/21 12:20 | Hannover 96 | Hamburger SV | 1-0 | 1 - 3 points |
| 2.BL | 05/12/21 12:30 | 05/12/21 12:20 | Dynamo Dresden | Karlsruher SC | 3-1 | 1 - 3 points |
| 2.BL | 05/12/21 12:30 | 05/12/21 12:20 | 1. FC Heidenheim 1846 | Jahn Regensburg | 3-0 | 1 - 3 points |
| GER1 | 05/12/21 14:30 | 05/12/21 14:20 | VfB Stuttgart | Hertha BSC | 2-2 | 3 - 5 points |
| GER1 | 05/12/21 16:30 | 05/12/21 16:20 | Bor. Mönchengladbach | SC Freiburg | 0-6 | 3 - 5 points |