Schedule
| Competition | Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|---|
| 2.BL | 19/11/21 17:30 | 19/11/21 17:20 | Hannover 96 | SC Paderborn 07 | 0-0 | 1 - 3 points |
| 2.BL | 19/11/21 17:30 | 19/11/21 17:20 | SV Sandhausen | 1. FC Nürnberg | 1-2 | 1 - 3 points |
| GER1 | 19/11/21 19:30 | 19/11/21 19:20 | FC Augsburg | FC Bayern Munich | 2-1 | 3 - 5 points |
| 2.BL | 20/11/21 12:30 | 20/11/21 12:20 | FC Hansa Rostock | Erzgebirge Aue | 1-2 | 1 - 3 points |
| 2.BL | 20/11/21 12:30 | 20/11/21 12:20 | Hamburger SV | Jahn Regensburg | 4-1 | 1 - 3 points |
| 2.BL | 20/11/21 12:30 | 20/11/21 12:20 | SV Darmstadt 98 | FC St. Pauli | 4-0 | 1 - 3 points |
| GER1 | 20/11/21 14:30 | 20/11/21 14:20 | Bor. Mönchengladbach | SpVgg Greuther Fürth | 4-0 | 3 - 5 points |
| GER1 | 20/11/21 14:30 | 20/11/21 14:20 | Bayer 04 Leverkusen | VfL Bochum | 1-0 | 3 - 5 points |
| GER1 | 20/11/21 14:30 | 20/11/21 14:20 | Borussia Dortmund | VfB Stuttgart | 2-1 | 3 - 5 points |
| GER1 | 20/11/21 14:30 | 20/11/21 14:20 | Arminia Bielefeld | VfL Wolfsburg | 2-2 | 3 - 5 points |
| GER1 | 20/11/21 14:30 | 20/11/21 14:20 | 1899 Hoffenheim | RB Leipzig | 2-0 | 3 - 5 points |
| GER1 | 20/11/21 17:30 | 20/11/21 17:20 | 1. FC Union Berlin | Hertha BSC | 2-0 | 3 - 5 points |
| 2.BL | 20/11/21 19:30 | 20/11/21 19:20 | Werder Bremen | FC Schalke 04 | 1-1 | 1 - 3 points |
| 2.BL | 21/11/21 12:30 | 21/11/21 12:20 | FC Ingolstadt | Karlsruher SC | 1-1 | 1 - 3 points |
| 2.BL | 21/11/21 12:30 | 21/11/21 12:20 | 1. FC Heidenheim 1846 | Holstein Kiel | 2-1 | 1 - 3 points |
| 2.BL | 21/11/21 12:30 | 21/11/21 12:20 | Dynamo Dresden | Fortuna Düsseldorf | 1-0 | 1 - 3 points |
| GER1 | 21/11/21 14:30 | 21/11/21 14:20 | SC Freiburg | Eintracht Frankfurt | 0-2 | 3 - 5 points |
| GER1 | 21/11/21 16:30 | 21/11/21 16:20 | FSV Mainz 05 | 1. FC Köln | 1-1 | 3 - 5 points |