Schedule
| Competition | Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|---|
| 2.BL | 05/11/21 17:30 | 05/11/21 17:20 | Holstein Kiel | Dynamo Dresden | 2-1 | 1 - 3 points |
| 2.BL | 05/11/21 17:30 | 05/11/21 17:20 | 1. FC Nürnberg | Werder Bremen | 1-2 | 1 - 3 points |
| GER1 | 05/11/21 19:30 | 05/11/21 19:20 | FSV Mainz 05 | Bor. Mönchengladbach | 1-1 | 3 - 5 points |
| 2.BL | 06/11/21 12:30 | 06/11/21 12:20 | Fortuna Düsseldorf | Hannover 96 | 1-1 | 1 - 3 points |
| 2.BL | 06/11/21 12:30 | 06/11/21 12:20 | SC Paderborn 07 | FC Ingolstadt | 2-1 | 1 - 3 points |
| 2.BL | 06/11/21 12:30 | 06/11/21 12:20 | Jahn Regensburg | FC Hansa Rostock | 2-3 | 1 - 3 points |
| GER1 | 06/11/21 14:30 | 06/11/21 14:20 | VfB Stuttgart | Arminia Bielefeld | 0-1 | 3 - 5 points |
| GER1 | 06/11/21 14:30 | 06/11/21 14:20 | VfL Wolfsburg | FC Augsburg | 1-0 | 3 - 5 points |
| GER1 | 06/11/21 14:30 | 06/11/21 14:20 | FC Bayern Munich | SC Freiburg | 2-1 | 3 - 5 points |
| GER1 | 06/11/21 14:30 | 06/11/21 14:20 | VfL Bochum | 1899 Hoffenheim | 2-0 | 3 - 5 points |
| GER1 | 06/11/21 17:30 | 06/11/21 17:20 | RB Leipzig | Borussia Dortmund | 2-1 | 3 - 5 points |
| 2.BL | 06/11/21 19:30 | 06/11/21 19:20 | Karlsruher SC | Hamburger SV | 1-1 | 1 - 3 points |
| 2.BL | 07/11/21 12:30 | 07/11/21 12:20 | Erzgebirge Aue | 1. FC Heidenheim 1846 | 2-0 | 1 - 3 points |
| 2.BL | 07/11/21 12:30 | 07/11/21 12:20 | FC Schalke 04 | SV Darmstadt 98 | 2-4 | 1 - 3 points |
| GER1 | 07/11/21 14:30 | 07/11/21 14:20 | Hertha BSC | Bayer 04 Leverkusen | 1-1 | 3 - 5 points |
| GER1 | 07/11/21 16:30 | 07/11/21 16:20 | 1. FC Köln | 1. FC Union Berlin | 2-2 | 3 - 5 points |
| GER1 | 07/11/21 18:30 | 07/11/21 18:20 | SpVgg Greuther Fürth | Eintracht Frankfurt | 1-2 | 3 - 5 points |
| 2.BL | 24/11/21 17:30 | 24/11/21 17:20 | FC St. Pauli | SV Sandhausen | 3-1 | 1 - 3 points |