Schedule
| Competition | Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|---|
| 2.BL | 15/10/21 17:30 | 15/10/21 17:20 | SC Paderborn 07 | Jahn Regensburg | 1-1 | 1 - 3 points |
| 2.BL | 15/10/21 17:30 | 15/10/21 17:20 | Hannover 96 | FC Schalke 04 | 0-1 | 1 - 3 points |
| GER1 | 15/10/21 19:30 | 15/10/21 19:20 | 1899 Hoffenheim | 1. FC Köln | 5-0 | 3 - 5 points |
| 2.BL | 16/10/21 12:30 | 16/10/21 12:20 | 1. FC Heidenheim 1846 | FC St. Pauli | 2-4 | 1 - 3 points |
| 2.BL | 16/10/21 12:30 | 16/10/21 12:20 | FC Ingolstadt | Holstein Kiel | 1-1 | 1 - 3 points |
| 2.BL | 16/10/21 12:30 | 16/10/21 12:20 | Karlsruher SC | Erzgebirge Aue | 2-1 | 1 - 3 points |
| GER1 | 16/10/21 14:30 | 16/10/21 14:20 | 1. FC Union Berlin | VfL Wolfsburg | 2-0 | 3 - 5 points |
| GER1 | 16/10/21 14:30 | 16/10/21 14:20 | Eintracht Frankfurt | Hertha BSC | 1-2 | 3 - 5 points |
| GER1 | 16/10/21 14:30 | 16/10/21 14:20 | Borussia Dortmund | FSV Mainz 05 | 3-1 | 3 - 5 points |
| GER1 | 16/10/21 14:30 | 16/10/21 14:20 | SpVgg Greuther Fürth | VfL Bochum | 0-1 | 3 - 5 points |
| GER1 | 16/10/21 14:30 | 16/10/21 14:20 | SC Freiburg | RB Leipzig | 1-1 | 3 - 5 points |
| GER1 | 16/10/21 17:30 | 16/10/21 17:20 | Bor. Mönchengladbach | VfB Stuttgart | 1-1 | 3 - 5 points |
| 2.BL | 16/10/21 19:30 | 16/10/21 19:20 | Hamburger SV | Fortuna Düsseldorf | 1-1 | 1 - 3 points |
| 2.BL | 17/10/21 12:30 | 17/10/21 12:20 | SV Darmstadt 98 | Werder Bremen | 3-0 | 1 - 3 points |
| 2.BL | 17/10/21 12:30 | 17/10/21 12:20 | Dynamo Dresden | 1. FC Nürnberg | 0-1 | 1 - 3 points |
| 2.BL | 17/10/21 12:30 | 17/10/21 12:20 | FC Hansa Rostock | SV Sandhausen | 1-1 | 1 - 3 points |
| GER1 | 17/10/21 14:30 | 17/10/21 14:20 | Bayer 04 Leverkusen | FC Bayern Munich | 1-5 | 3 - 5 points |
| GER1 | 17/10/21 16:30 | 17/10/21 16:20 | FC Augsburg | Arminia Bielefeld | 1-1 | 3 - 5 points |