| Date | Home | Away | Result |
|---|---|---|---|
| 25/10/25 14:00 | Sampdoria Genua | Frosinone Calcio | --- |
| 25/10/25 14:00 | FC Südtirol | FC Cesena | --- |
| 25/10/25 14:00 | AC Monza | AC Reggiana 1919 | --- |
| 25/10/25 14:00 | Padova Calcio | Juve Stabia | --- |
| 25/10/25 14:00 | US Avellino | Spezia Calcio | --- |
| 25/10/25 14:00 | SSC Bari | Mantova 1911 | --- |
| 25/10/25 14:00 | Virtus Entella | Pescara Calcio | --- |
| 25/10/25 14:00 | Modena FC | FC Empoli | --- |
| 25/10/25 14:00 | Carrarese Calcio 1908 | FC Venice | --- |
| 25/10/25 14:00 | US Catanzaro 1929 | Palermo FC | --- |
| 29/10/25 17:00 | FC Bologna | FC Turin | --- |
| 29/10/25 17:00 | Atalanta Bergamo | AC Milan | --- |
| 29/10/25 17:00 | Como Calcio | Hellas Verona | --- |
| 29/10/25 17:00 | Cagliari Calcio | Sassuolo Calcio | --- |
| 29/10/25 17:00 | Inter Milan | Fiorentina | --- |
| 29/10/25 17:00 | Genua CFC | US Cremonese | --- |
| 29/10/25 17:00 | US Lecce | SSC Napoli | --- |
| 29/10/25 17:00 | Juventus Turin | Udinese Calcio | --- |
| 29/10/25 17:00 | AS Roma | Parma Calcio 1913 | --- |
| 29/10/25 17:00 | Pisa Sporting Club | Lazio Rom | --- |