| Date | Home | Away | Result |
|---|---|---|---|
| 18/10/25 14:00 | Virtus Entella | Sampdoria Genua | --- |
| 18/10/25 14:00 | Frosinone Calcio | AC Monza | --- |
| 18/10/25 14:00 | US Catanzaro 1929 | Padova Calcio | --- |
| 18/10/25 14:00 | FC Empoli | FC Venice | --- |
| 18/10/25 14:00 | Palermo FC | Modena FC | --- |
| 18/10/25 14:00 | Pescara Calcio | Carrarese Calcio 1908 | --- |
| 18/10/25 14:00 | Juve Stabia | US Avellino | --- |
| 18/10/25 14:00 | Mantova 1911 | FC Südtirol | --- |
| 18/10/25 14:00 | AC Reggiana 1919 | SSC Bari | --- |
| 18/10/25 14:00 | Spezia Calcio | FC Cesena | --- |
| 26/10/25 17:00 | AC Milan | Pisa Sporting Club | --- |
| 26/10/25 17:00 | Lazio Rom | Juventus Turin | --- |
| 26/10/25 17:00 | Parma Calcio 1913 | Como Calcio | --- |
| 26/10/25 17:00 | SSC Napoli | Inter Milan | --- |
| 26/10/25 17:00 | FC Turin | Genua CFC | --- |
| 26/10/25 17:00 | Sassuolo Calcio | AS Roma | --- |
| 26/10/25 17:00 | Hellas Verona | Cagliari Calcio | --- |
| 26/10/25 17:00 | Udinese Calcio | US Lecce | --- |
| 26/10/25 17:00 | Fiorentina | FC Bologna | --- |
| 26/10/25 17:00 | US Cremonese | Atalanta Bergamo | --- |