| Date | Home | Away | Result |
|---|---|---|---|
| 04/10/25 14:00 | Modena FC | Virtus Entella | --- |
| 04/10/25 14:00 | AC Monza | US Catanzaro 1929 | --- |
| 04/10/25 14:00 | Carrarese Calcio 1908 | Juve Stabia | --- |
| 04/10/25 14:00 | FC Cesena | AC Reggiana 1919 | --- |
| 04/10/25 14:00 | FC Südtirol | FC Empoli | --- |
| 04/10/25 14:00 | FC Venice | Frosinone Calcio | --- |
| 04/10/25 14:00 | Sampdoria Genua | Pescara Calcio | --- |
| 04/10/25 14:00 | Spezia Calcio | Palermo FC | --- |
| 04/10/25 14:00 | US Avellino | Mantova 1911 | --- |
| 04/10/25 14:00 | SSC Bari | Padova Calcio | --- |
| 19/10/25 17:00 | Cagliari Calcio | FC Bologna | --- |
| 19/10/25 17:00 | Atalanta Bergamo | Lazio Rom | --- |
| 19/10/25 17:00 | US Cremonese | Udinese Calcio | --- |
| 19/10/25 17:00 | Como Calcio | Juventus Turin | --- |
| 19/10/25 17:00 | US Lecce | Sassuolo Calcio | --- |
| 19/10/25 17:00 | Genua CFC | Parma Calcio 1913 | --- |
| 19/10/25 17:00 | Pisa Sporting Club | Hellas Verona | --- |
| 19/10/25 17:00 | AC Milan | Fiorentina | --- |
| 19/10/25 17:00 | FC Turin | SSC Napoli | --- |
| 19/10/25 17:00 | AS Roma | Inter Milan | --- |