| Date | Home | Away | Result |
|---|---|---|---|
| 21/02/26 14:00 | Virtus Entella | US Catanzaro 1929 | --- |
| 21/02/26 14:00 | Frosinone Calcio | FC Empoli | --- |
| 21/02/26 14:00 | Carrarese Calcio 1908 | AC Monza | --- |
| 21/02/26 14:00 | FC Cesena | Spezia Calcio | --- |
| 21/02/26 14:00 | Padova Calcio | SSC Bari | --- |
| 21/02/26 14:00 | Palermo FC | FC Südtirol | --- |
| 21/02/26 14:00 | Juve Stabia | Modena FC | --- |
| 21/02/26 14:00 | Mantova 1911 | Sampdoria Genua | --- |
| 21/02/26 14:00 | AC Reggiana 1919 | US Avellino | --- |
| 21/02/26 14:00 | FC Venice | Pescara Calcio | --- |
| 22/02/26 17:00 | FC Bologna | Udinese Calcio | --- |
| 22/02/26 17:00 | Atalanta Bergamo | SSC Napoli | --- |
| 22/02/26 17:00 | Fiorentina | Pisa Sporting Club | --- |
| 22/02/26 17:00 | Cagliari Calcio | Lazio Rom | --- |
| 22/02/26 17:00 | Juventus Turin | Como Calcio | --- |
| 22/02/26 17:00 | Genua CFC | FC Turin | --- |
| 22/02/26 17:00 | AC Milan | Parma Calcio 1913 | --- |
| 22/02/26 17:00 | US Lecce | Inter Milan | --- |
| 22/02/26 17:00 | Sassuolo Calcio | Hellas Verona | --- |
| 22/02/26 17:00 | AS Roma | US Cremonese | --- |