| Date | Home | Away | Result |
|---|---|---|---|
| 13/02/26 19:45 | Pisa Sporting Club | AC Milan | 1-2 |
| 14/02/26 14:00 | Como Calcio | Fiorentina | 1-2 |
| 14/02/26 14:00 | Sampdoria Genua | Padova Calcio | 1-0 |
| 14/02/26 14:00 | Palermo FC | Virtus Entella | 3-0 |
| 14/02/26 14:00 | Modena FC | Carrarese Calcio 1908 | 2-0 |
| 14/02/26 16:15 | US Catanzaro 1929 | Mantova 1911 | 2-0 |
| 14/02/26 17:00 | Lazio Rom | Atalanta Bergamo | 0-2 |
| 14/02/26 18:30 | FC Cesena | FC Venice | 0-4 |
| 14/02/26 19:45 | Inter Milan | Juventus Turin | 3-2 |
| 15/02/26 11:30 | Udinese Calcio | Sassuolo Calcio | 1-2 |
| 15/02/26 14:00 | US Cremonese | Genua CFC | 0-0 |
| 15/02/26 14:00 | Parma Calcio 1913 | Hellas Verona | 2-1 |
| 15/02/26 14:00 | Spezia Calcio | Frosinone Calcio | 0-2 |
| 15/02/26 14:00 | AC Monza | Juve Stabia | 2-1 |
| 15/02/26 14:00 | SSC Bari | FC Südtirol | 1-2 |
| 15/02/26 16:15 | FC Empoli | AC Reggiana 1919 | 1-1 |
| 15/02/26 17:00 | FC Turin | FC Bologna | 1-2 |
| 15/02/26 18:30 | US Avellino | Pescara Calcio | 0-1 |
| 15/02/26 19:45 | SSC Napoli | AS Roma | 2-2 |
| 16/02/26 19:45 | Cagliari Calcio | US Lecce | 0-2 |