| Date | Home | Away | Result |
|---|---|---|---|
| 10/01/26 14:00 | Como Calcio | FC Bologna | 1-1 |
| 10/01/26 14:00 | Udinese Calcio | Pisa Sporting Club | 2-2 |
| 10/01/26 17:00 | AS Roma | Sassuolo Calcio | 2-0 |
| 10/01/26 19:45 | Atalanta Bergamo | FC Turin | 2-0 |
| 11/01/26 11:30 | US Lecce | Parma Calcio 1913 | 1-2 |
| 11/01/26 14:00 | Fiorentina | AC Milan | 1-1 |
| 11/01/26 17:00 | Hellas Verona | Lazio Rom | 0-1 |
| 11/01/26 19:45 | Inter Milan | SSC Napoli | 2-2 |
| 12/01/26 17:30 | Genua CFC | Cagliari Calcio | 3-0 |
| 12/01/26 19:45 | Juventus Turin | US Cremonese | 5-0 |
| 16/01/26 19:30 | Sampdoria Genua | Virtus Entella | 1-1 |
| 17/01/26 14:00 | FC Venice | US Catanzaro 1929 | 3-1 |
| 17/01/26 14:00 | FC Empoli | FC Südtirol | 0-1 |
| 17/01/26 14:00 | AC Monza | Frosinone Calcio | 2-2 |
| 17/01/26 14:00 | US Avellino | Carrarese Calcio 1908 | 1-2 |
| 17/01/26 14:00 | Padova Calcio | Mantova 1911 | 1-2 |
| 17/01/26 16:15 | AC Reggiana 1919 | FC Cesena | 1-2 |
| 17/01/26 18:30 | SSC Bari | Juve Stabia | 0-1 |
| 18/01/26 14:00 | Pescara Calcio | Modena FC | 0-2 |
| 18/01/26 16:15 | Palermo FC | Spezia Calcio | 1-0 |