| Date | Home | Away | Result |
|---|---|---|---|
| 29/08/25 17:30 | US Cremonese | Sassuolo Calcio | --- |
| 29/08/25 19:30 | AC Reggiana 1919 | FC Empoli | --- |
| 29/08/25 19:45 | US Lecce | AC Milan | --- |
| 30/08/25 17:30 | Parma Calcio 1913 | Atalanta Bergamo | --- |
| 30/08/25 17:30 | FC Bologna | Como Calcio | --- |
| 30/08/25 18:00 | Juve Stabia | FC Venice | --- |
| 30/08/25 18:00 | Mantova 1911 | Pescara Calcio | --- |
| 30/08/25 19:45 | SSC Napoli | Cagliari Calcio | --- |
| 30/08/25 19:45 | Pisa Sporting Club | AS Roma | --- |
| 30/08/25 20:00 | FC Cesena | Virtus Entella | --- |
| 30/08/25 20:00 | Palermo FC | Frosinone Calcio | --- |
| 30/08/25 20:00 | Spezia Calcio | US Catanzaro 1929 | --- |
| 31/08/25 17:30 | Genua CFC | Juventus Turin | --- |
| 31/08/25 17:30 | FC Turin | Fiorentina | --- |
| 31/08/25 18:00 | Carrarese Calcio 1908 | Padova Calcio | --- |
| 31/08/25 18:00 | FC Südtirol | Sampdoria Genua | --- |
| 31/08/25 19:45 | Lazio Rom | Hellas Verona | --- |
| 31/08/25 19:45 | Inter Milan | Udinese Calcio | --- |
| 31/08/25 20:00 | SSC Bari | AC Monza | --- |
| 31/08/25 20:00 | Modena FC | US Avellino | --- |