| Date | Home | Away | Result |
|---|---|---|---|
| 28/10/25 19:30 | Frosinone Calcio | Virtus Entella | --- |
| 28/10/25 19:30 | Juve Stabia | SSC Bari | --- |
| 28/10/25 19:30 | FC Cesena | Carrarese Calcio 1908 | --- |
| 28/10/25 19:30 | FC Empoli | Sampdoria Genua | --- |
| 28/10/25 19:30 | Pescara Calcio | US Avellino | --- |
| 28/10/25 19:30 | AC Reggiana 1919 | Modena FC | --- |
| 28/10/25 19:30 | Mantova 1911 | US Catanzaro 1929 | --- |
| 28/10/25 19:30 | Palermo FC | AC Monza | --- |
| 28/10/25 19:30 | Spezia Calcio | Padova Calcio | --- |
| 28/10/25 19:30 | FC Venice | FC Südtirol | --- |
| 02/11/25 17:00 | Hellas Verona | Inter Milan | --- |
| 02/11/25 17:00 | Udinese Calcio | Atalanta Bergamo | --- |
| 02/11/25 17:00 | Fiorentina | US Lecce | --- |
| 02/11/25 17:00 | US Cremonese | Juventus Turin | --- |
| 02/11/25 17:00 | AC Milan | AS Roma | --- |
| 02/11/25 17:00 | Lazio Rom | Cagliari Calcio | --- |
| 02/11/25 17:00 | Parma Calcio 1913 | FC Bologna | --- |
| 02/11/25 17:00 | SSC Napoli | Como Calcio | --- |
| 02/11/25 17:00 | FC Turin | Pisa Sporting Club | --- |
| 02/11/25 17:00 | Sassuolo Calcio | Genua CFC | --- |