Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 08/11/22 17:30 | 08/11/22 17:30 | FC St. Pauli | Holstein Kiel | 0-0 | 1 - 3 points |
| 08/11/22 17:30 | 08/11/22 17:30 | SC Paderborn 07 | Arminia Bielefeld | 0-2 | 1 - 3 points |
| 08/11/22 17:30 | 08/11/22 17:30 | 1. FC Kaiserslautern | Karlsruher SC | 2-0 | 1 - 3 points |
| 08/11/22 17:30 | 08/11/22 17:30 | Hannover 96 | Fortuna Düsseldorf | 2-0 | 1 - 3 points |
| 09/11/22 17:30 | 09/11/22 17:30 | SpVgg Greuther Fürth | Hamburger SV | 1-0 | 1 - 3 points |
| 09/11/22 17:30 | 09/11/22 17:30 | SV Sandhausen | 1. FC Heidenheim 1846 | 3-4 | 1 - 3 points |
| 09/11/22 17:30 | 09/11/22 17:30 | FC Hansa Rostock | 1. FC Nürnberg | 1-1 | 1 - 3 points |
| 09/11/22 17:30 | 09/11/22 17:30 | Jahn Regensburg | Eintracht Braunschweig | 1-1 | 1 - 3 points |
| 10/11/22 19:30 | 10/11/22 19:30 | 1. FC Magdeburg | SV Darmstadt 98 | 0-1 | 1 - 3 points |