Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 21/01/27 17:45 | 21/01/27 17:45 | Jagiellonia Bialystok | Olympique Lyon | --- | 5 - 7 points |
| 21/01/27 17:45 | 21/01/27 17:45 | NEC Nijmwegen | Benfica Lisbon | --- | 5 - 7 points |
| 21/01/27 17:45 | 21/01/27 17:45 | Besiktas Istanbul | Royale Union Saint-Gilloise | --- | 5 - 7 points |
| 21/01/27 17:45 | 21/01/27 17:45 | Ferencvaros Budapest | Juventus Turin | --- | 5 - 7 points |
| 21/01/27 17:45 | 21/01/27 17:45 | Olympiakos Piräus | 1899 Hoffenheim | --- | 5 - 7 points |
| 21/01/27 17:45 | 21/01/27 17:45 | Real Sociedad | Viktoria Plzen | --- | 5 - 7 points |
| 21/01/27 17:45 | 21/01/27 17:45 | FC Ararat-Armenia | NK Celje | --- | 5 - 7 points |
| 21/01/27 17:45 | 21/01/27 17:45 | Lillestroem SK | AFC Bournemouth | --- | 5 - 7 points |
| 21/01/27 17:45 | 21/01/27 17:45 | SK Sturm Graz | OFI Crete | --- | 5 - 7 points |
| 21/01/27 20:00 | 21/01/27 20:00 | Crystal Palace | Sparta Prag | --- | 5 - 7 points |
| 21/01/27 20:00 | 21/01/27 20:00 | Hapoel Beer Sheva | Celta Vigo | --- | 5 - 7 points |
| 21/01/27 20:00 | 21/01/27 20:00 | AZ Alkmaar | Dinamo Zagreb | --- | 5 - 7 points |
| 21/01/27 20:00 | 21/01/27 20:00 | RSC Anderlecht | AFC Sunderland | --- | 5 - 7 points |
| 21/01/27 20:00 | 21/01/27 20:00 | Stade Rennes | Omonia Nicosia | --- | 5 - 7 points |
| 21/01/27 20:00 | 21/01/27 20:00 | Celtic Glasgow | Olympique Marseille | --- | 5 - 7 points |
| 21/01/27 20:00 | 21/01/27 20:00 | Bayer 04 Leverkusen | FC Red Bull Salzburg | --- | 5 - 7 points |
| 21/01/27 20:00 | 21/01/27 20:00 | Lech Poznan | SCU Torreense | --- | 5 - 7 points |
| 21/01/27 20:00 | 21/01/27 20:00 | Levski Sofia | AC Milan | --- | 5 - 7 points |