Schedule
| Competition | Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|---|
| MLS | 02/04/22 20:30 | 02/04/22 20:30 | Chicago Fire | FC Dallas | 0-0 | 3 - 5 - 5 |
| MLS | 02/04/22 21:00 | 02/04/22 21:00 | Cincinnati FC | CF Montreal | 3-4 | 3 - 5 - 5 |
| MLS | 02/04/22 21:00 | 02/04/22 21:00 | Toronto FC | New York City FC | 2-1 | 4 - 5 - 3 |
| MLS | 02/04/22 23:00 | 02/04/22 23:00 | Columbus Crew | Nashville SC | 0-1 | 3 - 5 - 5 |
| MLS | 03/04/22 00:30 | 03/04/22 00:30 | New England Revolution | New York Red Bulls | 0-1 | 4 - 5 - 4 |
| MLS | 03/04/22 00:30 | 03/04/22 00:30 | Orlando City | Los Angeles FC | 2-4 | 4 - 5 - 4 |
| MLS | 03/04/22 00:30 | 03/04/22 00:30 | San Jose Earthquakes | Austin FC | 2-2 | 4 - 5 - 3 |
| MLS | 03/04/22 00:30 | 03/04/22 00:30 | D.C. United | Atlanta United FC | 0-1 | 3 - 5 - 4 |
| MLS | 03/04/22 00:30 | 03/04/22 00:30 | Philadelphia Union | Charlotte FC | 2-0 | 3 - 5 - 5 |
| MLS | 03/04/22 01:00 | 03/04/22 01:00 | Vancouver Whitecaps | Sporting Kansas City | 1-0 | 4 - 5 - 4 |
| MLS | 03/04/22 01:00 | 03/04/22 01:00 | Minnesota United FC | Seattle Sounders | 1-2 | 4 - 5 - 4 |
| MLS | 03/04/22 01:00 | 03/04/22 01:00 | Inter Miami CF | Houston Dynamo | 1-3 | 4 - 5 - 4 |
| MLS | 03/04/22 02:00 | 03/04/22 02:00 | Colorado Rapids | Real Salt Lake | 1-1 | 4 - 5 - 4 |
| MLS | 03/04/22 21:30 | 03/04/22 21:30 | Portland Timbers | Los Angeles Galaxy | 1-3 | 3 - 5 - 4 |