Schedule
| Competition | Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|---|
| MLS | 09/10/22 19:30 | 09/10/22 19:30 | Chicago Fire | New England Revolution | 1-1 | 3 - 5 - 4 |
| MLS | 09/10/22 19:30 | 09/10/22 19:30 | Inter Miami CF | CF Montreal | 1-3 | 3 - 5 - 4 |
| MLS | 09/10/22 19:30 | 09/10/22 19:30 | Atlanta United FC | New York City FC | 1-2 | 3 - 5 - 4 |
| MLS | 09/10/22 19:30 | 09/10/22 19:30 | Orlando City | Columbus Crew | 2-1 | 3 - 5 - 4 |
| MLS | 09/10/22 19:30 | 09/10/22 19:30 | D.C. United | Cincinnati FC | 2-5 | 4 - 5 - 3 |
| MLS | 09/10/22 19:30 | 09/10/22 19:30 | Philadelphia Union | Toronto FC | 4-0 | 3 - 5 - 5 |
| MLS | 09/10/22 19:30 | 09/10/22 19:30 | New York Red Bulls | Charlotte FC | 2-0 | 3 - 5 - 5 |
| MLS | 09/10/22 22:00 | 09/10/22 22:00 | Austin FC | Colorado Rapids | 1-1 | 3 - 5 - 5 |
| MLS | 09/10/22 22:00 | 09/10/22 22:00 | Los Angeles FC | Nashville SC | 0-1 | 3 - 5 - 5 |
| MLS | 09/10/22 22:00 | 09/10/22 22:00 | Houston Dynamo | Los Angeles Galaxy | 1-3 | 5 - 5 - 3 |
| MLS | 09/10/22 22:00 | 09/10/22 22:00 | Seattle Sounders | San Jose Earthquakes | 2-2 | 3 - 5 - 5 |
| MLS | 09/10/22 22:00 | 09/10/22 22:00 | Real Salt Lake | Portland Timbers | 3-1 | 3 - 5 - 5 |
| MLS | 09/10/22 22:00 | 09/10/22 22:00 | Minnesota United FC | Vancouver Whitecaps | 2-0 | 3 - 5 - 5 |
| MLS | 09/10/22 22:00 | 09/10/22 22:00 | FC Dallas | Sporting Kansas City | 2-1 | 3 - 5 - 5 |