Schedule
| Competition | Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|---|
| MLS | 17/09/22 18:00 | 17/09/22 18:00 | New York City FC | New York Red Bulls | 2-0 | 3 - 5 - 4 |
| MLS | 17/09/22 20:30 | 17/09/22 20:30 | Atlanta United FC | Philadelphia Union | 0-0 | 4 - 5 - 3 |
| MLS | 18/09/22 00:30 | 18/09/22 00:30 | New England Revolution | CF Montreal | 0-1 | 3 - 5 - 5 |
| MLS | 18/09/22 00:30 | 18/09/22 00:30 | Orlando City | Toronto FC | 4-0 | 3 - 5 - 5 |
| MLS | 18/09/22 01:00 | 18/09/22 01:00 | Chicago Fire | Charlotte FC | 2-3 | 3 - 5 - 4 |
| MLS | 18/09/22 01:30 | 18/09/22 01:30 | Sporting Kansas City | Minnesota United FC | 4-1 | 3 - 5 - 5 |
| MLS | 18/09/22 02:00 | 18/09/22 02:00 | Austin FC | Nashville SC | 1-1 | 3 - 5 - 5 |
| MLS | 18/09/22 02:30 | 18/09/22 02:30 | Real Salt Lake | Cincinnati FC | 1-2 | 3 - 5 - 5 |
| MLS | 18/09/22 03:00 | 18/09/22 03:00 | Vancouver Whitecaps | Seattle Sounders | 2-1 | 4 - 5 - 3 |
| MLS | 18/09/22 03:30 | 18/09/22 03:30 | San Jose Earthquakes | FC Dallas | 1-1 | 4 - 5 - 3 |
| MLS | 18/09/22 03:30 | 18/09/22 03:30 | Los Angeles Galaxy | Colorado Rapids | 4-1 | 3 - 5 - 5 |
| MLS | 18/09/22 18:00 | 18/09/22 18:00 | Columbus Crew | Portland Timbers | 1-1 | 3 - 5 - 5 |
| MLS | 18/09/22 22:00 | 18/09/22 22:00 | D.C. United | Inter Miami CF | 2-3 | 4 - 5 - 3 |
| MLS | 19/09/22 03:30 | 19/09/22 03:30 | Los Angeles FC | Houston Dynamo | 3-1 | 3 - 5 - 5 |