| Date | Home | Away | Result |
|---|---|---|---|
| 07/10/22 19:30 | 1899 Hoffenheim | Werder Bremen | 1-2 |
| 08/10/22 14:30 | VfL Bochum | Eintracht Frankfurt | 3-0 |
| 08/10/22 14:30 | Bayer 04 Leverkusen | FC Schalke 04 | 4-0 |
| 08/10/22 14:30 | FSV Mainz 05 | RB Leipzig | 1-1 |
| 08/10/22 14:30 | FC Augsburg | VfL Wolfsburg | 1-1 |
| 08/10/22 17:30 | Borussia Dortmund | FC Bayern Munich | 2-2 |
| 09/10/22 14:30 | Bor. Mönchengladbach | 1. FC Köln | 5-2 |
| 09/10/22 16:30 | Hertha BSC | SC Freiburg | 2-2 |
| 09/10/22 18:30 | VfB Stuttgart | 1. FC Union Berlin | 0-1 |