Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 24/09/21 18:00 | 24/09/21 18:00 | Altay SK | Besiktas Istanbul | 2-1 | 2 - 4 points |
| 25/09/21 11:30 | 25/09/21 11:30 | Sivasspor | Fatih Karagümrük | 4-0 | 2 - 4 points |
| 25/09/21 14:00 | 25/09/21 14:00 | Antalyaspor | Yeni Malatyaspor | 1-0 | 2 - 4 points |
| 25/09/21 17:00 | 25/09/21 17:00 | Adana Demirspor | Gazisehir Gaziantep FK | 4-0 | 2 - 4 points |
| 26/09/21 11:30 | 26/09/21 11:30 | Giresunspor | Kayserispor | 1-1 | 2 - 4 points |
| 26/09/21 14:00 | 26/09/21 14:00 | Istanbul Basaksehir FK | Caykur Rizespor | 3-0 | 2 - 4 points |
| 26/09/21 14:00 | 26/09/21 14:00 | Hatayspor | Fenerbahce Istanbul | 1-2 | 2 - 4 points |
| 26/09/21 17:00 | 26/09/21 17:00 | Galatasaray Istanbul | Göztepe Izmir | 2-1 | 2 - 4 points |
| 27/09/21 18:00 | 27/09/21 18:00 | Trabzonspor | Alanyaspor | 1-1 | 2 - 4 points |
| 27/09/21 18:00 | 27/09/21 18:00 | Kasimpasa Istanbul | Konyaspor | 2-2 | 2 - 4 points |