Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 21/09/21 15:00 | 21/09/21 15:00 | Caykur Rizespor | Altay SK | 1-2 | 2 - 4 points |
| 21/09/21 15:00 | 21/09/21 15:00 | Fatih Karagümrük | Antalyaspor | 0-0 | 2 - 4 points |
| 21/09/21 18:00 | 21/09/21 18:00 | Besiktas Istanbul | Adana Demirspor | 3-3 | 2 - 4 points |
| 21/09/21 18:00 | 21/09/21 18:00 | Yeni Malatyaspor | Sivasspor | 0-1 | 2 - 4 points |
| 22/09/21 15:00 | 22/09/21 15:00 | Gazisehir Gaziantep FK | Istanbul Basaksehir FK | 1-0 | 2 - 4 points |
| 22/09/21 18:00 | 22/09/21 18:00 | Göztepe Izmir | Hatayspor | 0-2 | 2 - 4 points |
| 22/09/21 18:00 | 22/09/21 18:00 | Kayserispor | Galatasaray Istanbul | 3-0 | 2 - 4 points |
| 23/09/21 15:00 | 23/09/21 15:00 | Konyaspor | Trabzonspor | 2-2 | 2 - 4 points |
| 23/09/21 18:00 | 23/09/21 18:00 | Fenerbahce Istanbul | Giresunspor | 2-1 | 2 - 4 points |
| 23/09/21 18:00 | 23/09/21 18:00 | Alanyaspor | Kasimpasa Istanbul | 2-0 | 2 - 4 points |