Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 11/09/21 15:00 | 11/09/21 15:00 | Fatih Karagümrük | Adana Demirspor | 4-0 | 2 - 4 points |
| 11/09/21 15:00 | 11/09/21 15:00 | Konyaspor | Altay SK | 3-1 | 2 - 4 points |
| 11/09/21 18:00 | 11/09/21 18:00 | Besiktas Istanbul | Yeni Malatyaspor | 3-0 | 2 - 4 points |
| 11/09/21 18:00 | 11/09/21 18:00 | Kayserispor | Kasimpasa Istanbul | 2-0 | 2 - 4 points |
| 12/09/21 15:00 | 12/09/21 15:00 | Caykur Rizespor | Hatayspor | 0-2 | 2 - 4 points |
| 12/09/21 15:00 | 12/09/21 15:00 | Fenerbahce Istanbul | Sivasspor | 1-1 | 2 - 4 points |
| 12/09/21 18:00 | 12/09/21 18:00 | Trabzonspor | Galatasaray Istanbul | 2-2 | 2 - 4 points |
| 12/09/21 18:00 | 12/09/21 18:00 | Göztepe Izmir | Istanbul Basaksehir FK | 2-1 | 2 - 4 points |
| 13/09/21 18:00 | 13/09/21 18:00 | Alanyaspor | Giresunspor | 1-0 | 2 - 4 points |
| 13/09/21 18:00 | 13/09/21 18:00 | Gazisehir Gaziantep FK | Antalyaspor | 2-0 | 2 - 4 points |