Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 21/09/21 19:00 | 21/09/21 19:00 | Valenciennes FC | SC Bastia | 2-1 | 5 - 7 points |
| 21/09/21 19:00 | 21/09/21 19:00 | AC Ajaccio | Chamois Niortais FC | 0-0 | 5 - 7 points |
| 21/09/21 19:00 | 21/09/21 19:00 | Amiens SC | Pau FC | 2-2 | 5 - 7 points |
| 21/09/21 19:00 | 21/09/21 19:00 | AJ Auxerre | Rodez Aveyron | 1-0 | 5 - 7 points |
| 21/09/21 19:00 | 21/09/21 19:00 | SM Caen | Dijon FCO | 0-1 | 5 - 7 points |
| 21/09/21 19:00 | 21/09/21 19:00 | USL Dunkerque | FC Toulouse | 0-2 | 5 - 7 points |
| 21/09/21 19:00 | 21/09/21 19:00 | Grenoble Foot | AS Nancy-Lorraine | 4-1 | 5 - 7 points |
| 21/09/21 19:00 | 21/09/21 19:00 | EA Guingamp | FC Sochaux | 1-2 | 5 - 7 points |
| 21/09/21 19:00 | 21/09/21 19:00 | Havre AC | US Quevilly Rouen | 1-0 | 5 - 7 points |
| 21/09/21 19:00 | 21/09/21 19:00 | Paris FC | Nimes Olympique | 2-0 | 5 - 7 points |