Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 18/09/21 14:00 | 18/09/21 14:00 | FC Sochaux | Paris FC | 2-0 | 5 - 7 points |
| 18/09/21 14:00 | 18/09/21 14:00 | FC Toulouse | Grenoble Foot | 4-1 | 5 - 7 points |
| 18/09/21 18:00 | 18/09/21 18:00 | SC Bastia | SM Caen | 1-1 | 5 - 7 points |
| 18/09/21 18:00 | 18/09/21 18:00 | Nimes Olympique | Amiens SC | 3-3 | 5 - 7 points |
| 18/09/21 18:00 | 18/09/21 18:00 | Chamois Niortais FC | EA Guingamp | 2-0 | 5 - 7 points |
| 18/09/21 18:00 | 18/09/21 18:00 | Pau FC | Valenciennes FC | 1-1 | 5 - 7 points |
| 18/09/21 18:00 | 18/09/21 18:00 | US Quevilly Rouen | AJ Auxerre | 0-0 | 5 - 7 points |
| 18/09/21 18:00 | 18/09/21 18:00 | Rodez Aveyron | AC Ajaccio | 0-2 | 5 - 7 points |
| 18/09/21 18:00 | 18/09/21 18:00 | Dijon FCO | USL Dunkerque | 2-0 | 5 - 7 points |
| 18/09/21 18:00 | 18/09/21 18:00 | AS Nancy-Lorraine | Havre AC | 1-1 | 5 - 7 points |