Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 11/09/21 14:00 | 11/09/21 14:00 | Paris FC | EA Guingamp | 0-1 | 5 - 7 points |
| 11/09/21 18:00 | 11/09/21 18:00 | Dijon FCO | SC Bastia | 2-1 | 5 - 7 points |
| 11/09/21 18:00 | 11/09/21 18:00 | AC Ajaccio | FC Sochaux | 1-0 | 5 - 7 points |
| 11/09/21 18:00 | 11/09/21 18:00 | Amiens SC | Rodez Aveyron | 0-1 | 5 - 7 points |
| 11/09/21 18:00 | 11/09/21 18:00 | AJ Auxerre | Chamois Niortais FC | 4-0 | 5 - 7 points |
| 11/09/21 18:00 | 11/09/21 18:00 | SM Caen | Pau FC | 1-2 | 5 - 7 points |
| 11/09/21 18:00 | 11/09/21 18:00 | USL Dunkerque | AS Nancy-Lorraine | 0-0 | 5 - 7 points |
| 11/09/21 18:00 | 11/09/21 18:00 | Grenoble Foot | Nimes Olympique | 2-1 | 5 - 7 points |
| 11/09/21 18:00 | 11/09/21 18:00 | Valenciennes FC | US Quevilly Rouen | 1-2 | 5 - 7 points |
| 13/09/21 19:45 | 13/09/21 19:45 | Havre AC | FC Toulouse | 1-1 | 5 - 7 points |