Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 20/11/21 14:00 | 20/11/21 14:00 | FC Toulouse | FC Sochaux | 4-1 | 5 - 7 points |
| 20/11/21 18:00 | 20/11/21 18:00 | Pau FC | EA Guingamp | 2-0 | 5 - 7 points |
| 20/11/21 18:00 | 20/11/21 18:00 | SC Bastia | Chamois Niortais FC | 2-0 | 5 - 7 points |
| 20/11/21 18:00 | 20/11/21 18:00 | Valenciennes FC | Grenoble Foot | 1-0 | 5 - 7 points |
| 20/11/21 18:00 | 20/11/21 18:00 | SM Caen | Paris FC | 0-1 | 5 - 7 points |
| 20/11/21 18:00 | 20/11/21 18:00 | USL Dunkerque | AC Ajaccio | 0-1 | 5 - 7 points |
| 20/11/21 18:00 | 20/11/21 18:00 | Havre AC | Amiens SC | 1-1 | 5 - 7 points |
| 20/11/21 18:00 | 20/11/21 18:00 | AS Nancy-Lorraine | Rodez Aveyron | 0-2 | 5 - 7 points |
| 20/11/21 18:00 | 20/11/21 18:00 | Nimes Olympique | US Quevilly Rouen | 2-1 | 5 - 7 points |
| 22/11/21 19:45 | 22/11/21 19:45 | Dijon FCO | AJ Auxerre | 3-1 | 5 - 7 points |