Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 21/10/25 17:45 | 21/10/25 17:45 | FC Barcelona | Olympiakos Piräus | --- | 5 - 7 points |
| 21/10/25 17:45 | 21/10/25 17:45 | Qairat Almaty | Pafos FC | --- | 5 - 7 points |
| 21/10/25 20:00 | 21/10/25 20:00 | PSV Eindhoven | SSC Napoli | --- | 5 - 7 points |
| 21/10/25 20:00 | 21/10/25 20:00 | FC Villarreal | Manchester City | --- | 5 - 7 points |
| 21/10/25 20:00 | 21/10/25 20:00 | FC Copenhagen | Borussia Dortmund | --- | 5 - 7 points |
| 21/10/25 20:00 | 21/10/25 20:00 | Royale Union Saint-Gilloise | Inter Milan | --- | 5 - 7 points |
| 21/10/25 20:00 | 21/10/25 20:00 | Arsenal FC | Atletico Madrid | --- | 5 - 7 points |
| 21/10/25 20:00 | 21/10/25 20:00 | Newcastle United | Benfica Lisbon | --- | 5 - 7 points |
| 21/10/25 20:00 | 21/10/25 20:00 | Bayer 04 Leverkusen | Paris St. Germain | --- | 5 - 7 points |
| 22/10/25 17:45 | 22/10/25 17:45 | Galatasaray Istanbul | FK Bodö/Glimt | --- | 5 - 7 points |
| 22/10/25 17:45 | 22/10/25 17:45 | Athletic Bilbao | Qarabag | --- | 5 - 7 points |
| 22/10/25 20:00 | 22/10/25 20:00 | Real Madrid | Juventus Turin | --- | 5 - 7 points |
| 22/10/25 20:00 | 22/10/25 20:00 | FC Bayern Munich | Club Brugge | --- | 5 - 7 points |
| 22/10/25 20:00 | 22/10/25 20:00 | Chelsea FC | Ajax Amsterdam | --- | 5 - 7 points |
| 22/10/25 20:00 | 22/10/25 20:00 | Eintracht Frankfurt | Liverpool FC | --- | 5 - 7 points |
| 22/10/25 20:00 | 22/10/25 20:00 | Atalanta Bergamo | Slavia Prag | --- | 5 - 7 points |
| 22/10/25 20:00 | 22/10/25 20:00 | Sporting Lisbon | Olympique Marseille | --- | 5 - 7 points |
| 22/10/25 20:00 | 22/10/25 20:00 | AS Monaco | Tottenham Hotspur | --- | 5 - 7 points |