| Date | Home | Away | Result |
|---|---|---|---|
| 20/01/26 15:30 | Kairat Almaty | Club Brugge | --- |
| 20/01/26 17:45 | FK Bodö/Glimt | Manchester City | --- |
| 20/01/26 20:00 | FC Copenhagen | SSC Napoli | --- |
| 20/01/26 20:00 | Tottenham Hotspur | Borussia Dortmund | --- |
| 20/01/26 20:00 | Real Madrid | AS Monaco | --- |
| 20/01/26 20:00 | Inter Milan | Arsenal FC | --- |
| 20/01/26 20:00 | Olympiakos Piräus | Bayer 04 Leverkusen | --- |
| 20/01/26 20:00 | FC Villarreal | Ajax Amsterdam | --- |
| 20/01/26 20:00 | Sporting Lisbon | Paris St. Germain | --- |
| 21/01/26 17:45 | Galatasaray Istanbul | Atletico Madrid | --- |
| 21/01/26 17:45 | Qarabag | Eintracht Frankfurt | --- |
| 21/01/26 20:00 | Slavia Prag | FC Barcelona | --- |
| 21/01/26 20:00 | Atalanta Bergamo | Athletic Bilbao | --- |
| 21/01/26 20:00 | Newcastle United | PSV Eindhoven | --- |
| 21/01/26 20:00 | FC Bayern Munich | Royale Union Saint-Gilloise | --- |
| 21/01/26 20:00 | Olympique Marseille | Liverpool FC | --- |
| 21/01/26 20:00 | Juventus Turin | Benfica Lisbon | --- |
| 21/01/26 20:00 | Chelsea FC | Pafos FC | --- |