Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 26/12/21 17:00 | 26/12/21 17:00 | USA Perpignan | Castres Olympique | 19-20 | 4 - 10 - 4 |
| 27/12/21 18:00 | 27/12/21 18:00 | Biarritz | Montpellier Hérault RC | 12-27 | 5 - 10 - 3 |
| 27/12/21 20:05 | 27/12/21 20:05 | Atlantique Stade Rochelais | Lyon OU | 25-3 | 3 - 10 - 10 |
| 11/02/22 20:05 | 11/02/22 20:05 | Stade Toulousain | Stade Français | 28-29 | 3 - 10 - 10 |
| 12/02/22 13:15 | 12/02/22 13:15 | Racing Métro 92 | Section Paloise | 35-29 | 3 - 10 - 10 |
| 12/02/22 14:05 | 12/02/22 14:05 | CA Brive | ASM Clermont Auvergne | 27-20 | 4 - 10 - 4 |
| 12/02/22 20:05 | 12/02/22 20:05 | RC Toulon | Union Bordeaux Bègles | 21-18 | 4 - 10 - 4 |