Schedule
| Competition | Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|---|
| 2.BL | 29/04/22 17:30 | 29/04/22 16:30 | 1. FC Heidenheim 1846 | Fortuna Düsseldorf | 1-3 | 2 - 4 points |
| 2.BL | 29/04/22 17:30 | 29/04/22 16:30 | FC St. Pauli | 1. FC Nürnberg | 1-1 | 2 - 4 points |
| 2.BL | 29/04/22 17:30 | 29/04/22 16:30 | Hannover 96 | Karlsruher SC | 2-0 | 2 - 4 points |
| 2.BL | 29/04/22 17:30 | 29/04/22 16:30 | SV Sandhausen | FC Schalke 04 | 1-2 | 2 - 4 points |
| 2.BL | 29/04/22 17:30 | 29/04/22 16:30 | Werder Bremen | Holstein Kiel | 2-3 | 2 - 4 points |
| GER1 | 29/04/22 19:30 | 29/04/22 18:30 | 1. FC Union Berlin | SpVgg Greuther Fürth | 1-1 | 2 - 4 points |
| 2.BL | 30/04/22 12:30 | 30/04/22 11:30 | Dynamo Dresden | Jahn Regensburg | 1-1 | 2 - 4 points |
| 2.BL | 30/04/22 12:30 | 30/04/22 11:30 | FC Hansa Rostock | SC Paderborn 07 | 0-0 | 2 - 4 points |
| 2.BL | 30/04/22 12:30 | 30/04/22 11:30 | FC Ingolstadt | Hamburger SV | 0-4 | 2 - 4 points |
| GER1 | 30/04/22 14:30 | 30/04/22 13:30 | Arminia Bielefeld | Hertha BSC | 1-1 | 2 - 4 points |
| GER1 | 30/04/22 14:30 | 30/04/22 13:30 | FC Augsburg | 1. FC Köln | 1-4 | 2 - 4 points |
| GER1 | 30/04/22 14:30 | 30/04/22 13:30 | FSV Mainz 05 | FC Bayern Munich | 3-1 | 2 - 4 points |
| GER1 | 30/04/22 14:30 | 30/04/22 13:30 | VfB Stuttgart | VfL Wolfsburg | 1-1 | 2 - 4 points |
| GER1 | 30/04/22 14:30 | 30/04/22 13:30 | Borussia Dortmund | VfL Bochum | 3-4 | 2 - 4 points |
| GER1 | 30/04/22 17:30 | 30/04/22 16:30 | 1899 Hoffenheim | SC Freiburg | 3-4 | 2 - 4 points |
| 2.BL | 30/04/22 19:30 | 30/04/22 18:30 | SV Darmstadt 98 | Erzgebirge Aue | 6-0 | 2 - 4 points |
| RLNO | 01/05/22 12:00 | 01/05/22 11:00 | Energie Cottbus | SV Lichtenberg 47 | 4-1 | 2 - 4 points |
| GER1 | 02/05/22 19:30 | 02/05/22 18:30 | Bor. Mönchengladbach | RB Leipzig | 3-1 | 2 - 4 points |
| GER1 | 02/05/22 19:30 | 02/05/22 18:30 | Bayer 04 Leverkusen | Eintracht Frankfurt | 2-0 | 2 - 4 points |