Schedule
| Competition | Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|---|
| 2.BL | 19/11/21 17:30 | 19/11/21 16:30 | Hannover 96 | SC Paderborn 07 | 0-0 | 2 - 4 points |
| 2.BL | 19/11/21 17:30 | 19/11/21 16:30 | SV Sandhausen | 1. FC Nürnberg | 1-2 | 2 - 4 points |
| GER1 | 19/11/21 19:30 | 19/11/21 18:30 | FC Augsburg | FC Bayern Munich | 2-1 | 2 - 4 points |
| RLNO | 20/11/21 12:00 | 20/11/21 11:00 | Energie Cottbus | Hertha BSC II | 2-2 | 2 - 4 points |
| 2.BL | 20/11/21 12:30 | 20/11/21 11:30 | FC Hansa Rostock | Erzgebirge Aue | 1-2 | 2 - 4 points |
| 2.BL | 20/11/21 12:30 | 20/11/21 11:30 | Hamburger SV | Jahn Regensburg | 4-1 | 2 - 4 points |
| 2.BL | 20/11/21 12:30 | 20/11/21 11:30 | SV Darmstadt 98 | FC St. Pauli | 4-0 | 2 - 4 points |
| GER1 | 20/11/21 14:30 | 20/11/21 13:30 | Bor. Mönchengladbach | SpVgg Greuther Fürth | 4-0 | 2 - 4 points |
| GER1 | 20/11/21 14:30 | 20/11/21 13:30 | Bayer 04 Leverkusen | VfL Bochum | 1-0 | 2 - 4 points |
| GER1 | 20/11/21 14:30 | 20/11/21 13:30 | Borussia Dortmund | VfB Stuttgart | 2-1 | 2 - 4 points |
| GER1 | 20/11/21 14:30 | 20/11/21 13:30 | Arminia Bielefeld | VfL Wolfsburg | 2-2 | 2 - 4 points |
| GER1 | 20/11/21 14:30 | 20/11/21 13:30 | 1899 Hoffenheim | RB Leipzig | 2-0 | 2 - 4 points |
| GER1 | 20/11/21 17:30 | 20/11/21 16:30 | 1. FC Union Berlin | Hertha BSC | 2-0 | 2 - 4 points |
| 2.BL | 20/11/21 19:30 | 20/11/21 18:30 | Werder Bremen | FC Schalke 04 | 1-1 | 2 - 4 points |
| 2.BL | 21/11/21 12:30 | 21/11/21 11:30 | FC Ingolstadt | Karlsruher SC | 1-1 | 2 - 4 points |
| 2.BL | 21/11/21 12:30 | 21/11/21 11:30 | 1. FC Heidenheim 1846 | Holstein Kiel | 2-1 | 2 - 4 points |
| 2.BL | 21/11/21 12:30 | 21/11/21 11:30 | Dynamo Dresden | Fortuna Düsseldorf | 1-0 | 2 - 4 points |
| GER1 | 21/11/21 14:30 | 21/11/21 13:30 | SC Freiburg | Eintracht Frankfurt | 0-2 | 2 - 4 points |
| GER1 | 21/11/21 16:30 | 21/11/21 15:30 | FSV Mainz 05 | 1. FC Köln | 1-1 | 2 - 4 points |