Schedule
| Competition | Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|---|
| ESP2 | 10/09/21 20:00 | 10/09/21 20:00 | Sporting Gijon | CD Leganes | 2-1 | 3 - 5 points |
| ESP2 | 11/09/21 15:00 | 11/09/21 15:00 | SD Amorebieta | Burgos CF | 2-2 | 3 - 5 points |
| ESP2 | 11/09/21 15:00 | 11/09/21 15:00 | Real Sociedad B | SD Eibar | 2-3 | 3 - 5 points |
| ESP2 | 11/09/21 17:15 | 11/09/21 17:15 | UD Las Palmas | UD Ibiza Eivissa | 1-1 | 3 - 5 points |
| ESP2 | 11/09/21 20:00 | 11/09/21 20:00 | CD Mirandes | AD Alcorcon | 1-3 | 3 - 5 points |
| ESP2 | 12/09/21 13:00 | 12/09/21 13:00 | Real Oviedo | FC Cartagena | 2-0 | 3 - 5 points |
| ESP2 | 12/09/21 15:00 | 12/09/21 15:00 | Real Valladolid | CD Teneriffa | 0-2 | 3 - 5 points |
| ESP2 | 12/09/21 17:15 | 12/09/21 17:15 | SD Ponferradina | UD Almeria | 1-0 | 3 - 5 points |
| ESP2 | 12/09/21 19:30 | 12/09/21 19:30 | CF Fuenlabrada | Real Saragossa | 1-1 | 3 - 5 points |
| ESP2 | 12/09/21 20:30 | 12/09/21 20:30 | FC Malaga | FC Girona | 2-0 | 3 - 5 points |
| ESP2 | 13/09/21 20:00 | 13/09/21 20:00 | CD Lugo | SD Huesca | 3-2 | 3 - 5 points |