Schedule
| Competition | Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|---|
| ESP2 | 27/08/21 19:00 | 27/08/21 19:00 | UD Las Palmas | SD Huesca | 2-1 | 3 - 5 points |
| ESP2 | 27/08/21 21:00 | 27/08/21 21:00 | FC Malaga | AD Alcorcon | 1-0 | 3 - 5 points |
| ESP2 | 28/08/21 16:00 | 28/08/21 16:00 | Sporting Gijon | CD Mirandes | 2-1 | 3 - 5 points |
| ESP2 | 28/08/21 18:30 | 28/08/21 18:30 | CD Leganes | UD Ibiza Eivissa | 1-2 | 3 - 5 points |
| ESP2 | 28/08/21 18:30 | 28/08/21 18:30 | Real Oviedo | CD Teneriffa | 0-0 | 3 - 5 points |
| ESP2 | 28/08/21 21:00 | 28/08/21 21:00 | SD Ponferradina | FC Girona | 2-1 | 3 - 5 points |
| ESP2 | 29/08/21 16:00 | 29/08/21 16:00 | SD Amorebieta | UD Almeria | 2-1 | 3 - 5 points |
| ESP2 | 29/08/21 18:30 | 29/08/21 18:30 | Real Sociedad B | CF Fuenlabrada | 0-0 | 3 - 5 points |
| ESP2 | 29/08/21 18:30 | 29/08/21 18:30 | CD Lugo | Real Valladolid | 0-2 | 3 - 5 points |
| ESP2 | 29/08/21 21:00 | 29/08/21 21:00 | Burgos CF | SD Eibar | 0-1 | 3 - 5 points |
| ESP2 | 30/08/21 21:00 | 30/08/21 21:00 | Real Saragossa | FC Cartagena | 0-1 | 3 - 5 points |