Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 07/10/22 01:15 | 07/10/22 01:15 | Denver Broncos | Indianapolis Colts | 9-12OT | 3 - 10 - 7 |
| 09/10/22 14:30 | 09/10/22 14:30 | Green Bay Packers | New York Giants | 22-27 | 3 - 10 - 10 |
| 09/10/22 18:00 | 09/10/22 18:00 | Buffalo Bills | Pittsburgh Steelers | 38-3 | 3 - 10 - 10 |
| 09/10/22 18:00 | 09/10/22 18:00 | Tampa Bay Buccaneers | Atlanta Falcons | 21-15 | 3 - 10 - 10 |
| 09/10/22 18:00 | 09/10/22 18:00 | Washington Commanders | Tennessee Titans | 17-21 | 6 - 10 - 3 |
| 09/10/22 18:00 | 09/10/22 18:00 | New Orleans Saints | Seattle Seahawks | 39-32 | 4 - 10 - 4 |
| 09/10/22 18:00 | 09/10/22 18:00 | New York Jets | Miami Dolphins | 40-17 | 6 - 10 - 3 |
| 09/10/22 18:00 | 09/10/22 18:00 | Cleveland Browns | Los Angeles Chargers | 28-30 | 6 - 10 - 3 |
| 09/10/22 18:00 | 09/10/22 18:00 | New England Patriots | Detroit Lions | 29-0 | 4 - 10 - 5 |
| 09/10/22 18:00 | 09/10/22 18:00 | Minnesota Vikings | Chicago Bears | 29-22 | 3 - 10 - 7 |
| 09/10/22 18:00 | 09/10/22 18:00 | Jacksonville Jaguars | Houston Texans | 6-13 | 3 - 10 - 10 |
| 09/10/22 21:05 | 09/10/22 21:05 | Carolina Panthers | San Francisco 49ers | 15-37 | 10 - 10 - 3 |
| 09/10/22 21:25 | 09/10/22 21:25 | Arizona Cardinals | Philadelphia Eagles | 17-20 | 5 - 10 - 3 |
| 09/10/22 21:25 | 09/10/22 21:25 | Los Angeles Rams | Dallas Cowboys | 10-22 | 3 - 10 - 7 |
| 10/10/22 01:20 | 10/10/22 01:20 | Baltimore Ravens | Cincinnati Bengals | 19-17 | 4 - 10 - 5 |
| 11/10/22 01:15 | 11/10/22 01:15 | Kansas City Chiefs | Las Vegas Raiders | 30-29 | 3 - 10 - 10 |