Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 05/11/21 00:20 | 05/11/21 00:20 | Indianapolis Colts | New York Jets | 45-30 | 3 - 10 - 10 |
| 07/11/21 18:00 | 07/11/21 18:00 | New York Giants | Las Vegas Raiders | 23-16 | 8 - 10 - 3 |
| 07/11/21 18:00 | 07/11/21 18:00 | Miami Dolphins | Houston Texans | 17-9 | 3 - 10 - 6 |
| 07/11/21 18:00 | 07/11/21 18:00 | Jacksonville Jaguars | Buffalo Bills | 9-6 | 10 - 10 - 3 |
| 07/11/21 18:00 | 07/11/21 18:00 | Cincinnati Bengals | Cleveland Browns | 16-41 | 4 - 10 - 5 |
| 07/11/21 18:00 | 07/11/21 18:00 | Baltimore Ravens | Minnesota Vikings | 34-31OT | 3 - 10 - 10 |
| 07/11/21 18:00 | 07/11/21 18:00 | Carolina Panthers | New England Patriots | 6-24 | 5 - 10 - 4 |
| 07/11/21 18:00 | 07/11/21 18:00 | Dallas Cowboys | Denver Broncos | 16-30 | 3 - 10 - 10 |
| 07/11/21 18:00 | 07/11/21 18:00 | New Orleans Saints | Atlanta Falcons | 25-27 | 3 - 10 - 10 |
| 07/11/21 21:05 | 07/11/21 21:05 | Philadelphia Eagles | Los Angeles Chargers | 24-27 | 6 - 10 - 3 |
| 07/11/21 21:25 | 07/11/21 21:25 | San Francisco 49ers | Arizona Cardinals | 17-31 | 6 - 10 - 3 |
| 07/11/21 21:25 | 07/11/21 21:25 | Kansas City Chiefs | Green Bay Packers | 13-7 | 4 - 10 - 4 |
| 08/11/21 01:20 | 08/11/21 01:20 | Los Angeles Rams | Tennessee Titans | 16-28 | 3 - 10 - 9 |
| 09/11/21 01:15 | 09/11/21 01:15 | Pittsburgh Steelers | Chicago Bears | 29-27 | 3 - 10 - 10 |