Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 02/12/25 17:45 | 02/12/25 17:45 | Elverum Håndball | Fram | 38-24 | 2 - 17 points |
| 02/12/25 17:45 | 02/12/25 17:45 | Fredericia HK | IK Sävehof | 29-33 | 2 - 17 points |
| 02/12/25 17:45 | 02/12/25 17:45 | HC Kriens-Luzern | Porto | 25-44 | 2 - 17 points |
| 02/12/25 17:45 | 02/12/25 17:45 | IFK Kristianstad | Sesvete | 28-27 | 2 - 17 points |
| 02/12/25 17:45 | 02/12/25 17:45 | Potaissa Turda | St. Raphael | 25-34 | 2 - 17 points |
| 02/12/25 17:45 | 02/12/25 17:45 | Presov | TSV Hannover-Burgdorf | 29-37 | 2 - 17 points |
| 02/12/25 17:45 | 02/12/25 17:45 | SG Flensburg-Handewitt | CD Bidasoa Irún | 38-35 | 2 - 17 points |
| 02/12/25 17:45 | 02/12/25 17:45 | Vardar 1961 | Toulouse | 37-35 | 2 - 17 points |
| 02/12/25 19:45 | 02/12/25 19:45 | Benfica | MT Melsungen | 26-30 | 2 - 17 points |
| 02/12/25 19:45 | 02/12/25 19:45 | BM Granollers | Minaur Baia Mare | 29-28 | 2 - 17 points |
| 02/12/25 19:45 | 02/12/25 19:45 | BSV Bern Muri | Ostrow Wielkopolski | 28-28 | 2 - 17 points |
| 02/12/25 19:45 | 02/12/25 19:45 | Kadetten Schaffhausen | Partizan | 32-19 | 2 - 17 points |
| 02/12/25 19:45 | 02/12/25 19:45 | Karlskrona | Ferencváros | 31-32 | 2 - 17 points |
| 02/12/25 19:45 | 02/12/25 19:45 | RK Našice | Ademar León | 29-28 | 2 - 17 points |
| 02/12/25 19:45 | 02/12/25 19:45 | Slovan | Skanderborg AGF | 30-37 | 2 - 17 points |
| 02/12/25 19:45 | 02/12/25 19:45 | THW Kiel | Montpellier Handball | 27-18 | 2 - 17 points |