Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 14/10/25 17:45 | 14/10/25 17:45 | Ferencváros | Karlskrona | 31-29 | 2 - 17 points |
| 14/10/25 17:45 | 14/10/25 17:45 | Fredericia HK | TSV Hannover-Burgdorf | 29-31 | 2 - 17 points |
| 14/10/25 17:45 | 14/10/25 17:45 | Kadetten Schaffhausen | Ademar León | 30-22 | 2 - 17 points |
| 14/10/25 17:45 | 14/10/25 17:45 | Montpellier Handball | THW Kiel | 28-30 | 2 - 17 points |
| 14/10/25 17:45 | 14/10/25 17:45 | MT Melsungen | Benfica | 28-26 | 2 - 17 points |
| 14/10/25 17:45 | 14/10/25 17:45 | Potaissa Turda | CD Bidasoa Irún | 33-34 | 2 - 17 points |
| 14/10/25 17:45 | 14/10/25 17:45 | Presov | IK Sävehof | 30-30 | 2 - 17 points |
| 14/10/25 17:45 | 14/10/25 17:45 | Vardar 1961 | Sesvete | 34-29 | 2 - 17 points |
| 14/10/25 19:45 | 14/10/25 19:45 | RK Našice | Partizan | 30-22 | 2 - 17 points |
| 14/10/25 19:45 | 14/10/25 19:45 | BM Granollers | Skanderborg AGF | 26-31 | 2 - 17 points |
| 14/10/25 19:45 | 14/10/25 19:45 | Elverum Håndball | HC Kriens-Luzern | 31-34 | 2 - 17 points |
| 14/10/25 19:45 | 14/10/25 19:45 | Fram | Porto | 26-38 | 2 - 17 points |
| 14/10/25 19:45 | 14/10/25 19:45 | Ostrow Wielkopolski | BSV Bern Muri | 32-28 | 2 - 17 points |
| 14/10/25 19:45 | 14/10/25 19:45 | SG Flensburg-Handewitt | St. Raphael | 32-30 | 2 - 17 points |
| 14/10/25 19:45 | 14/10/25 19:45 | Slovan | Minaur Baia Mare | 35-29 | 2 - 17 points |
| 14/10/25 19:45 | 14/10/25 19:45 | Toulouse | IFK Kristianstad | 28-30 | 2 - 17 points |