Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 04/02/22 20:00 | 04/02/22 20:00 | Manchester United | Middlesbrough FC | 8-9a.PSO | 5 - 7 points |
| 05/02/22 12:30 | 05/02/22 12:30 | Kidderminster Harriers | West Ham United | 1-2a.e.t | 5 - 7 points |
| 05/02/22 12:30 | 05/02/22 12:30 | Chelsea FC | Plymouth Argyle | 2-1a.e.t | 5 - 7 points |
| 05/02/22 15:00 | 05/02/22 15:00 | Crystal Palace | Hartlepool United | 2-0 | 5 - 7 points |
| 05/02/22 15:00 | 05/02/22 15:00 | Everton FC | Brentford FC | 4-1 | 5 - 7 points |
| 05/02/22 15:00 | 05/02/22 15:00 | Stoke City | Wigan Athletic | 2-0 | 5 - 7 points |
| 05/02/22 15:00 | 05/02/22 15:00 | Peterborough United | Queens Park Rangers | 2-0 | 5 - 7 points |
| 05/02/22 15:00 | 05/02/22 15:00 | Manchester City | Fulham FC | 4-1 | 5 - 7 points |
| 05/02/22 15:00 | 05/02/22 15:00 | Southampton FC | Coventry City | 2-1a.e.t | 5 - 7 points |
| 05/02/22 15:00 | 05/02/22 15:00 | Huddersfield Town | Barnsley FC | 1-0 | 5 - 7 points |
| 05/02/22 15:00 | 05/02/22 15:00 | Wolverhampton Wanderers | Norwich City | 0-1 | 5 - 7 points |
| 05/02/22 17:30 | 05/02/22 17:30 | Cambridge United | Luton Town | 0-3 | 5 - 7 points |
| 05/02/22 20:00 | 05/02/22 20:00 | Tottenham Hotspur | Brighton and Hove Albion | 3-1 | 5 - 7 points |
| 06/02/22 12:00 | 06/02/22 12:00 | Liverpool FC | Cardiff City | 3-1 | 5 - 7 points |
| 06/02/22 16:00 | 06/02/22 16:00 | Nottingham Forest | Leicester City | 4-1 | 5 - 7 points |
| 06/02/22 18:30 | 06/02/22 18:30 | AFC Bournemouth | Boreham Wood | 0-1 | 5 - 7 points |