Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 07/01/22 20:00 | 07/01/22 20:00 | Swindon Town | Manchester City | 1-4 | 5 - 7 points |
| 08/01/22 12:15 | 08/01/22 12:15 | Mansfield Town | Middlesbrough FC | 2-3 | 5 - 7 points |
| 08/01/22 12:30 | 08/01/22 12:30 | Burnley FC | Huddersfield Town | 1-2 | 5 - 7 points |
| 08/01/22 12:30 | 08/01/22 12:30 | Bristol City | Fulham FC | 0-1a.e.t | 5 - 7 points |
| 08/01/22 12:30 | 08/01/22 12:30 | Hartlepool United | FC Blackpool | 2-1 | 5 - 7 points |
| 08/01/22 12:30 | 08/01/22 12:30 | Coventry City | Derby County | 1-0 | 5 - 7 points |
| 08/01/22 12:45 | 08/01/22 12:45 | Millwall FC | Crystal Palace | 1-2 | 5 - 7 points |
| 08/01/22 15:00 | 08/01/22 15:00 | Boreham Wood | AFC Wimbledon | 2-0 | 5 - 7 points |
| 08/01/22 15:00 | 08/01/22 15:00 | Peterborough United | Bristol Rovers | 2-1 | 5 - 7 points |
| 08/01/22 15:00 | 08/01/22 15:00 | Leicester City | Watford FC | 4-1 | 5 - 7 points |
| 08/01/22 15:00 | 08/01/22 15:00 | FC Port Vale | Brentford FC | 1-4 | 5 - 7 points |
| 08/01/22 15:00 | 08/01/22 15:00 | Queens Park Rangers | Rotherham United | 9-8a.PSO | 5 - 7 points |
| 08/01/22 15:00 | 08/01/22 15:00 | Barnsley FC | Barrow FC | 5-4a.e.t | 5 - 7 points |
| 08/01/22 15:00 | 08/01/22 15:00 | Kidderminster Harriers | Reading FC | 2-1 | 5 - 7 points |
| 08/01/22 15:00 | 08/01/22 15:00 | West Bromwich Albion | Brighton and Hove Albion | 1-2a.e.t | 5 - 7 points |
| 08/01/22 15:00 | 08/01/22 15:00 | Newcastle United | Cambridge United | 0-1 | 5 - 7 points |
| 08/01/22 15:00 | 08/01/22 15:00 | Wigan Athletic | Blackburn Rovers | 3-2 | 5 - 7 points |
| 08/01/22 17:30 | 08/01/22 17:30 | Swansea City | Southampton FC | 2-3a.e.t | 5 - 7 points |
| 08/01/22 17:30 | 08/01/22 17:30 | Hull City A.F.C. | Everton FC | 2-3a.e.t | 5 - 7 points |
| 08/01/22 17:30 | 08/01/22 17:30 | Birmingham City | Plymouth Argyle | 0-1a.e.t | 5 - 7 points |
| 08/01/22 17:30 | 08/01/22 17:30 | Chelsea FC | FC Chesterfield | 5-1 | 5 - 7 points |
| 08/01/22 17:45 | 08/01/22 17:45 | Yeovil Town | AFC Bournemouth | 1-3 | 5 - 7 points |
| 09/01/22 12:30 | 09/01/22 12:30 | Luton Town | Harrogate Town FC | 4-0 | 5 - 7 points |
| 09/01/22 14:00 | 09/01/22 14:00 | Tottenham Hotspur | FC Morecambe | 3-1 | 5 - 7 points |
| 09/01/22 14:00 | 09/01/22 14:00 | Stoke City | Leyton Orient | 2-0 | 5 - 7 points |
| 09/01/22 14:00 | 09/01/22 14:00 | Liverpool FC | Shrewsbury Town | 4-1 | 5 - 7 points |
| 09/01/22 14:00 | 09/01/22 14:00 | Cardiff City | Preston North End | 2-1a.e.t | 5 - 7 points |
| 09/01/22 14:00 | 09/01/22 14:00 | Charlton Athletic | Norwich City | 0-1 | 5 - 7 points |
| 09/01/22 14:00 | 09/01/22 14:00 | Wolverhampton Wanderers | Sheffield United | 3-0 | 5 - 7 points |
| 09/01/22 14:00 | 09/01/22 14:00 | West Ham United | Leeds United | 2-0 | 5 - 7 points |
| 09/01/22 17:10 | 09/01/22 17:10 | Nottingham Forest | Arsenal FC | 1-0 | 5 - 7 points |
| 10/01/22 19:55 | 10/01/22 19:55 | Manchester United | Aston Villa | 1-0 | 5 - 7 points |