Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 03/12/21 19:45 | 03/12/21 19:45 | Rotherham United | Stockport County | 1-0 | 5 - 7 points |
| 03/12/21 19:45 | 03/12/21 19:45 | FC Gateshead | Charlton Athletic | 0-2 | 5 - 7 points |
| 04/12/21 12:45 | 04/12/21 12:45 | Buxton FC | FC Morecambe | 0-1 | 5 - 7 points |
| 04/12/21 15:00 | 04/12/21 15:00 | FC Portsmouth | Harrogate Town FC | 1-2 | 5 - 7 points |
| 04/12/21 15:00 | 04/12/21 15:00 | Bristol Rovers | Sutton United | 2-1 | 5 - 7 points |
| 04/12/21 15:00 | 04/12/21 15:00 | FC Walsall | Swindon Town | 1-2 | 5 - 7 points |
| 04/12/21 15:00 | 04/12/21 15:00 | Ipswich Town | Barrow FC | 0-0 | 5 - 7 points |
| 04/12/21 15:00 | 04/12/21 15:00 | Lincoln City | Hartlepool United | 0-1 | 5 - 7 points |
| 04/12/21 15:00 | 04/12/21 15:00 | Cambridge United | Exeter City | 2-1 | 5 - 7 points |
| 04/12/21 15:00 | 04/12/21 15:00 | Burton Albion | FC Port Vale | 1-2 | 5 - 7 points |
| 04/12/21 15:00 | 04/12/21 15:00 | Carlisle United | Shrewsbury Town | 1-2 | 5 - 7 points |
| 04/12/21 15:00 | 04/12/21 15:00 | Doncaster Rovers | Mansfield Town | 2-3 | 5 - 7 points |
| 04/12/21 15:00 | 04/12/21 15:00 | Leyton Orient | Tranmere Rovers | 4-0 | 5 - 7 points |
| 04/12/21 15:00 | 04/12/21 15:00 | AFC Wimbledon | Cheltenham Town | 4-3 | 5 - 7 points |
| 04/12/21 17:30 | 04/12/21 17:30 | Yeovil Town | Stevenage FC | 1-0 | 5 - 7 points |
| 05/12/21 12:15 | 05/12/21 12:15 | FC Rochdale | Plymouth Argyle | 1-2 | 5 - 7 points |
| 05/12/21 12:30 | 05/12/21 12:30 | Colchester United | Wigan Athletic | 1-2 | 5 - 7 points |
| 05/12/21 16:00 | 05/12/21 16:00 | Kidderminster Harriers | Halifax Town | 2-0 | 5 - 7 points |
| 05/12/21 17:15 | 05/12/21 17:15 | Salford City | FC Chesterfield | 0-2 | 5 - 7 points |
| 06/12/21 19:45 | 06/12/21 19:45 | Boreham Wood | St Albans City | 4-0 | 5 - 7 points |