| Date | Home | Away | Result |
|---|---|---|---|
| 30/09/22 19:30 | FC Bayern Munich | Bayer 04 Leverkusen | 4-0 |
| 01/10/22 14:30 | RB Leipzig | VfL Bochum | 4-0 |
| 01/10/22 14:30 | SC Freiburg | FSV Mainz 05 | 2-1 |
| 01/10/22 14:30 | 1. FC Köln | Borussia Dortmund | 3-2 |
| 01/10/22 14:30 | VfL Wolfsburg | VfB Stuttgart | 3-2 |
| 01/10/22 14:30 | Eintracht Frankfurt | 1. FC Union Berlin | 2-0 |
| 01/10/22 17:30 | Werder Bremen | Bor. Mönchengladbach | 5-1 |
| 02/10/22 14:35 | Hertha BSC | 1899 Hoffenheim | 1-1 |
| 02/10/22 16:30 | FC Schalke 04 | FC Augsburg | 2-3 |