| Date | Home | Away | Result |
|---|---|---|---|
| 09/09/22 19:30 | Werder Bremen | FC Augsburg | 0-1 |
| 10/09/22 14:30 | Eintracht Frankfurt | VfL Wolfsburg | 0-1 |
| 10/09/22 14:30 | RB Leipzig | Borussia Dortmund | 3-0 |
| 10/09/22 14:30 | FC Bayern Munich | VfB Stuttgart | 2-2 |
| 10/09/22 14:30 | Hertha BSC | Bayer 04 Leverkusen | 2-2 |
| 10/09/22 14:30 | 1899 Hoffenheim | FSV Mainz 05 | 4-1 |
| 10/09/22 17:30 | FC Schalke 04 | VfL Bochum | 3-1 |
| 11/09/22 14:30 | 1. FC Köln | 1. FC Union Berlin | 0-1 |
| 11/09/22 16:30 | SC Freiburg | Bor. Mönchengladbach | 0-0 |