| Date | Home | Away | Result |
|---|---|---|---|
| 21/10/22 19:30 | FSV Mainz 05 | 1. FC Köln | 5-0 |
| 22/10/22 14:30 | SC Freiburg | Werder Bremen | 2-0 |
| 22/10/22 14:30 | 1899 Hoffenheim | FC Bayern Munich | 0-2 |
| 22/10/22 14:30 | FC Augsburg | RB Leipzig | 3-3 |
| 22/10/22 14:30 | Borussia Dortmund | VfB Stuttgart | 5-0 |
| 22/10/22 14:30 | Bayer 04 Leverkusen | VfL Wolfsburg | 2-2 |
| 22/10/22 17:30 | Bor. Mönchengladbach | Eintracht Frankfurt | 1-3 |
| 23/10/22 14:30 | VfL Bochum | 1. FC Union Berlin | 2-1 |
| 23/10/22 16:30 | Hertha BSC | FC Schalke 04 | 2-1 |