Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 15/04/22 18:00 | 15/04/22 18:00 | Spezia Calcio | Inter Milan | 1-3 | 2 - 5 points |
| 15/04/22 20:00 | 15/04/22 20:00 | AC Milan | FC Genua 1893 | 2-0 | 2 - 5 points |
| 16/04/22 11:30 | 16/04/22 11:30 | Cagliari Calcio | Sassuolo Calcio | 1-0 | 2 - 5 points |
| 16/04/22 13:30 | 16/04/22 13:30 | Sampdoria Genua | US Salernitana | 1-2 | 2 - 5 points |
| 16/04/22 13:30 | 16/04/22 13:30 | Udinese Calcio | FC Empoli | 4-1 | 2 - 5 points |
| 16/04/22 15:30 | 16/04/22 15:30 | Fiorentina | FC Venice | 1-0 | 2 - 5 points |
| 16/04/22 17:30 | 16/04/22 17:30 | Juventus Turin | FC Bologna | 1-1 | 2 - 5 points |
| 16/04/22 19:45 | 16/04/22 19:45 | Lazio Rom | FC Turin | 1-1 | 2 - 5 points |
| 18/04/22 18:00 | 18/04/22 18:00 | SSC Napoli | AS Roma | 1-1 | 2 - 5 points |
| 18/04/22 20:00 | 18/04/22 20:00 | Atalanta Bergamo | Hellas Verona | 1-2 | 2 - 5 points |