Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 09/04/22 14:00 | 09/04/22 14:00 | FC Empoli | Spezia Calcio | 0-0 | 2 - 5 points |
| 09/04/22 17:00 | 09/04/22 17:00 | Inter Milan | Hellas Verona | 2-0 | 2 - 5 points |
| 09/04/22 19:45 | 09/04/22 19:45 | Cagliari Calcio | Juventus Turin | 1-2 | 2 - 5 points |
| 10/04/22 11:30 | 10/04/22 11:30 | FC Genua 1893 | Lazio Rom | 1-4 | 2 - 5 points |
| 10/04/22 14:00 | 10/04/22 14:00 | Sassuolo Calcio | Atalanta Bergamo | 2-1 | 2 - 5 points |
| 10/04/22 14:00 | 10/04/22 14:00 | SSC Napoli | Fiorentina | 2-3 | 2 - 5 points |
| 10/04/22 14:00 | 10/04/22 14:00 | FC Venice | Udinese Calcio | 1-2 | 2 - 5 points |
| 10/04/22 17:00 | 10/04/22 17:00 | AS Roma | US Salernitana | 2-1 | 2 - 5 points |
| 10/04/22 19:45 | 10/04/22 19:45 | FC Turin | AC Milan | 0-0 | 2 - 5 points |
| 11/04/22 19:45 | 11/04/22 19:45 | FC Bologna | Sampdoria Genua | 2-0 | 2 - 5 points |