Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 25/02/22 17:50 | 25/02/22 17:50 | AC Milan | Udinese Calcio | 1-1 | 2 - 5 points |
| 25/02/22 20:05 | 25/02/22 20:05 | FC Genua 1893 | Inter Milan | 0-0 | 2 - 5 points |
| 26/02/22 14:05 | 26/02/22 14:05 | US Salernitana | FC Bologna | 1-1 | 2 - 5 points |
| 26/02/22 17:05 | 26/02/22 17:05 | FC Empoli | Juventus Turin | 2-3 | 2 - 5 points |
| 26/02/22 19:50 | 26/02/22 19:50 | Sassuolo Calcio | Fiorentina | 2-1 | 2 - 5 points |
| 27/02/22 11:35 | 27/02/22 11:35 | FC Turin | Cagliari Calcio | 1-2 | 2 - 5 points |
| 27/02/22 14:05 | 27/02/22 14:05 | Hellas Verona | FC Venice | 3-1 | 2 - 5 points |
| 27/02/22 17:05 | 27/02/22 17:05 | Spezia Calcio | AS Roma | 0-1 | 2 - 5 points |
| 27/02/22 19:50 | 27/02/22 19:50 | Lazio Rom | SSC Napoli | 1-2 | 2 - 5 points |
| 28/02/22 19:50 | 28/02/22 19:50 | Atalanta Bergamo | Sampdoria Genua | 4-0 | 2 - 5 points |