Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 04/12/21 14:00 | 04/12/21 14:00 | AC Milan | US Salernitana | 2-0 | 2 - 5 points |
| 04/12/21 17:00 | 04/12/21 17:00 | AS Roma | Inter Milan | 0-3 | 2 - 5 points |
| 04/12/21 19:45 | 04/12/21 19:45 | SSC Napoli | Atalanta Bergamo | 2-3 | 2 - 5 points |
| 05/12/21 11:30 | 05/12/21 11:30 | FC Bologna | Fiorentina | 2-3 | 2 - 5 points |
| 05/12/21 14:00 | 05/12/21 14:00 | Spezia Calcio | Sassuolo Calcio | 2-2 | 2 - 5 points |
| 05/12/21 14:00 | 05/12/21 14:00 | FC Venice | Hellas Verona | 3-4 | 2 - 5 points |
| 05/12/21 17:00 | 05/12/21 17:00 | Sampdoria Genua | Lazio Rom | 1-3 | 2 - 5 points |
| 05/12/21 19:45 | 05/12/21 19:45 | Juventus Turin | FC Genua 1893 | 2-0 | 2 - 5 points |
| 06/12/21 17:30 | 06/12/21 17:30 | FC Empoli | Udinese Calcio | 3-1 | 2 - 5 points |
| 06/12/21 19:45 | 06/12/21 19:45 | Cagliari Calcio | FC Turin | 1-1 | 2 - 5 points |