Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 20/11/21 14:00 | 20/11/21 14:00 | Atalanta Bergamo | Spezia Calcio | 5-2 | 2 - 5 points |
| 20/11/21 17:00 | 20/11/21 17:00 | Lazio Rom | Juventus Turin | 0-2 | 2 - 5 points |
| 20/11/21 19:45 | 20/11/21 19:45 | Fiorentina | AC Milan | 4-3 | 2 - 5 points |
| 21/11/21 11:30 | 21/11/21 11:30 | Sassuolo Calcio | Cagliari Calcio | 2-2 | 2 - 5 points |
| 21/11/21 14:00 | 21/11/21 14:00 | FC Bologna | FC Venice | 0-1 | 2 - 5 points |
| 21/11/21 14:00 | 21/11/21 14:00 | US Salernitana | Sampdoria Genua | 0-2 | 2 - 5 points |
| 21/11/21 17:00 | 21/11/21 17:00 | Inter Milan | SSC Napoli | 3-2 | 2 - 5 points |
| 21/11/21 19:45 | 21/11/21 19:45 | FC Genua 1893 | AS Roma | 0-2 | 2 - 5 points |
| 22/11/21 17:30 | 22/11/21 17:30 | Hellas Verona | FC Empoli | 2-1 | 2 - 5 points |
| 22/11/21 19:45 | 22/11/21 19:45 | FC Turin | Udinese Calcio | 2-1 | 2 - 5 points |