Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 10/09/21 20:00 | 10/09/21 20:00 | FC Lorient | OSC Lille | 2-1 | 2 - 5 points |
| 11/09/21 16:00 | 11/09/21 16:00 | Paris St. Germain | Clermont Foot | 4-0 | 2 - 5 points |
| 11/09/21 20:00 | 11/09/21 20:00 | AS Monaco | Olympique Marseille | 0-2 | 2 - 5 points |
| 12/09/21 12:00 | 12/09/21 12:00 | HSC Montpellier | AS St. Etienne | 2-0 | 2 - 5 points |
| 12/09/21 14:00 | 12/09/21 14:00 | Girondins Bordeaux | RC Lens | 2-3 | 2 - 5 points |
| 12/09/21 14:00 | 12/09/21 14:00 | Stade Brest 29 | SCO Angers | 1-1 | 2 - 5 points |
| 12/09/21 14:00 | 12/09/21 14:00 | FC Metz | ES Troyes AC | 0-2 | 2 - 5 points |
| 12/09/21 14:00 | 12/09/21 14:00 | Stade Rennes | Stade Reims | 0-2 | 2 - 5 points |
| 12/09/21 16:05 | 12/09/21 16:05 | FC Nantes | OGC Nice | 0-2 | 2 - 5 points |
| 12/09/21 19:45 | 12/09/21 19:45 | Olympique Lyon | Racing Club Strasbourg | 3-1 | 2 - 5 points |